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1

Syntheses of water-soluble [60]fullerene derivatives and their enhancing effect on neurite outgrowth in NGF-treated PC12 cells

Hiroki Tsumoto, Syo Kawahara, Yuki Fujisawa, Takayoshi Suzuki, Hidehiko Nakagawa, Kohfuku Kohda, Naoki Miyata

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 484 KB

english, 2010

2

Formation of 2′-Deoxy-2-nitroadenosines by Reaction of 2′-Deoxyadenosines with Copper(II) Nitrate/Acetic Anhydride.

Toyo Kaiya, Haruko Tanaka, Kohfuku Kohda

Journal:

Year:

2003

File:

PDF, 114 KB

2003

3

Product Analyses of Ozone Mediated Nitration of Benzimidazole Derivatives with Nitrogen Dioxide: Formation of 1-Nitrobenzimidazoles and Conversion to Benzotriazoles

Kaiya, Toyo, Nakamura, Kei, Tanaka, Masaru, Miyata, Naoki, Kohda, Kohfuku

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

2004

Language:

english

File:

PDF, 116 KB

english, 2004

4

Enhanced Cytotoxicity of Some Triterpenes toward Leukemia L1210 Cells Cultured in Low pH Media: Possibility of a New Mode of Cell Killing.

NODA, Yasuhiro, KAIYA, Toyo, KOHDA, Kohfuku, KAWAZOE, Yutaka

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1997

File:

PDF, 805 KB

1997

5

Preparation of C60-based active esters and coupling of C60 moiety to amines or alcohols

Hiroki Tsumoto, Katsumasa Takahashi, Takayoshi Suzuki, Hidehiko Nakagawa, Kohfuku Kohda, Naoki Miyata

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 151 KB

english, 2008

6

Electrophilic amination of guanine derivatives. Mechanism for formation of 8-aminoguanine derivatives

Kohfuku Kohda, Kunihisa Baba, Yutaka Kawazoe

Journal:

Year:

1990

Language:

english

File:

PDF, 674 KB

english, 1990

7

Selective desilylation of phenolic and alcoholic trimethylsilyl ethers

Yutaka Kawazoe, Makoto Nomura, Yumiko Kondo, Kohfuku Kohda

Journal:

Tetrahedron Letters

Year:

1987

Language:

english

File:

PDF, 250 KB

english, 1987

8

Preparation of (R)-N-methylsalsolinol via reversed-phase high-performance liquid chromatography using β-cyclodextrin as a mobile-phase additive

Chiyoko Minami, Yulin Deng, Fumi Urano, Toyo Kaiya, Kohfuku Kohda, Masao Kawai, Makoto Naoi

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Year:

1997

Language:

english

File:

PDF, 96 KB

english, 1997

9

Mutagenicity of a series of N-alkyl-, N-hydroxyalkyl-, N-haloalkyl- and N-carboxyalkyl-N-nitrosoureas in Escherichia coli tester strains: Dependence on the uvrA DNA-repair system

Kohfuku H. Kohda, Shin-ichi Ninomiya, Kinya Washizu, Kazuo Shiraki, Masakazu Ebie, Yutaka Kawazoe

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1987

Language:

english

File:

PDF, 758 KB

english, 1987

10

Wide difference between the cytotoxicity of the 11-α- and 11-β-cyano analogues of tilivalline and their epimeric conversion

Kohfuku Kohda, Naoto Yamagami, Toshio Kasamatsu, Toyohiko Aoyama, Takayuki Shioiri

Journal:

Biochemical Pharmacology

Year:

1995

Language:

english

File:

PDF, 486 KB

english, 1995

11

Thiol-Based SAHA Analogues as Potent Histone Deacetylase Inhibitors.

Takayoshi Suzuki, Akiyasu Kouketsu, Azusa Matsuura, Arihiro Kohara, Shin-ichi Ninomiya, Kohfuku Kohda, Naoki Miyata

Journal:

Year:

2004

File:

PDF, 13 KB

2004

12

Cytotoxic activity of cyclic peptides of marine origin and their derivatives: importance of oxazoline functions

Takayuki Shioiri, Yasumasa Hamada, Shinji Kato, Makoto Shibata, Yutaka Kondo, Hiroaki Nakagawa, Kohfuku Kohda

Journal:

Biochemical Pharmacology

Year:

1987

Language:

english

File:

PDF, 406 KB

english, 1987

13

Inhibition of Human O 6 -Alkylguanine-DNA Alkyltransferase and Potentiation of the Cytotoxicity of Chloroethylnitrosourea by 4(6)-(Benzyloxy)-2,6(4)-diamino-5-(nitro or nitroso)pyrimidine Derivatives and Analogues

Terashima, Isamu, Kohda, Kohfuku

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 134 KB

english, 1998

14

FORMATION OF 2?-DEOXY-2-NITROADENOSINES BY REACTION OF 2?-DEOXYADENOSINES WITH COPPER(II) NITRATE/ACETIC ANHYDRIDE

Kaiya, Toyo, Tanaka, Haruko, Kohda, Kohfuku

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2002

Language:

english

File:

PDF, 171 KB

english, 2002

15

CytA Protein, a .DELTA.-Endotoxin of Bacillus thuringiensis subsp. israelensis Is Associated with DNA.

YOKOYAMA, Yumi, KOHDA, Kohfuku, OKAMOTO, Masaji

Journal:

Biological & Pharmaceutical Bulletin

Year:

1998

File:

PDF, 950 KB

1998

16

Singlet oxygen takes part in 8-hydroxydeoxyguanosine formation in deoxyribonucleic acid treated with the horseradish peroxidase-H2O2 system.

KOHDA, Kohfuku, NAKAGAWA, Takashi, KAWAZOE, Yutaka

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1990

File:

PDF, 611 KB

1990

17

Inhibitory Effect of Fatty Acids on 8-Hydroxydeoxyguanosine Formation in Calf Thymus DNA Treated with Bleomycin-Fe(II).

KASAMATSU, Toshio, NAKAGAWA, Takashi, KOHDA, Kohfuku

Journal:

Biological & Pharmaceutical Bulletin

Year:

1994

File:

PDF, 736 KB

1994

18

A novel enzyme enantio-selectively synthesizes (R)salsolinol, a precursor of a dopaminergic neurotoxin, N-methyl(R)salsolinol

Makoto Naoi, Wakako Maruyama, Philippe Dostert, Kohfuku Kohda, Toyo Kaiya

Journal:

Neuroscience Letters

Year:

1996

Language:

english

File:

PDF, 368 KB

english, 1996

19

Synthesis of Oligodeoxynucleotides Containing a Single 6α- or 6β-Diastereoisomer of N 2 -(Estradiol-6-yl)-2‘-deoxyguanosine

Itoh, Shinji, Shibutani, Shinya, Ikegami, Masazumi, Watanabe, Shingo, Laxmi, Y. R. Santosh, Suzuki, Naomi, Kohda, Kohfuku, Takanashi, Kaori, Yoshizawa, Itsuo

Journal:

Chemical Research in Toxicology

Year:

2006

Language:

english

File:

PDF, 133 KB

english, 2006

20

Synthesis, Miscoding Specificity, and Thermodynamic Stability of Oligodeoxynucleotide Containing 8-Methyl-2‘-deoxyguanosine

Kohda, Kohfuku, Tsunomoto, Hirotaka, Minoura, Yasushi, Tanabe, Kazushi, Shibutani, Shinya

Journal:

Chemical Research in Toxicology

Year:

1996

Language:

english

File:

PDF, 415 KB

english, 1996

21

ChemInform Abstract: Reactions of Chloride Salts of 7-Amino-9-ethylguanine and 1-Amino-3-methylbenzimidazoles with Lead(IV) Acetate: Formation of 8-Aza-9-ethylguanine and 1-Methyl-1H-benzotriazoles.

Toyo Kaiya, Shinsuke Aoyama, Kohfuku Kohda

Journal:

Year:

1999

File:

PDF, 29 KB

1999

22

Synthesis and properties of N-aminoguanines

Kohfuku Kohda, Moriyoshi Yasuda, Hiroshi Ukai, Kunihisa Baba, Yuriko Yamagata, Yutaka Kawazoe

Journal:

Year:

1989

Language:

english

File:

PDF, 538 KB

english, 1989

23

Temperature-dependence of cytotoxicity of several genotoxicants in chinese hamster V79 cells: Bleomycin, paraquat, and some N-alkyl-N-nitrosoureas

Takayoshi Suzuki, Kohfuku Kohda, Yutaka Kawazoe

Journal:

Biochemical and Biophysical Research Communications

Year:

1987

Language:

english

File:

PDF, 342 KB

english, 1987

24

Mouse methyltransferase for repair of O 6 -methylguanine and O 4 -methylthymine in DNA

Kawate, Hisaya, Ihara, Kenji, Kohda, Kohfuku, Sakumi, Kunihiko, Sekiguchi, Mutsuo

Journal:

Year:

1995

Language:

english

File:

PDF, 6.50 MB

english, 1995

25

Studies on chemical carcinogens and mutagens. XXXIII. Mutation frequencies induced by combinations of methylating and/or ethylating mutagens.

KAWAZOE, YUTAKA, HAKURA, ATSUSHI, KOHDA, KOHFUKU

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1986

File:

PDF, 656 KB

1986

26

Formation of O6, 7-dimethylguanine residues in calf thymus deoxyribonucleic acid treated with carcinogenic N-methyl-N-nitrosourea in vitro.

KOHDA, Kohfuku, SAWADA, Noriaki, KAWAZOE, Yutaka

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1991

File:

PDF, 388 KB

1991

27

Lignified natural products as potential medicinal resources. I. Potentiation of hemolytic plaque-forming cell production in mice.

OH-HARA, Toshinari, IKEDA, Yoshiaki, SAKAGAMI, Hiroshi, KONNO, Kunio, KAIYA, Toyo, KOHDA, Kohfuku, KAWAZOE, Yutaka

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1990

File:

PDF, 465 KB

1990

28

Deprivation of the mutagenic property of quinoline. Inhibition of mutagenic metabolism by fluorine substitution.

Takahashi, Kazuhiko, Kamiya, Masatsugu, Sengoku, Yoko, Kohda, Kohfuku, Kawazoe, Yutaka

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1988

Language:

english

File:

PDF, 580 KB

english, 1988

29

Studies on chemical carcinogens. XXIV. Mutagenic potency of alkylated 4-nitroquinoline 1-oxides: Its dependence on the rate of metabolic activation.

TAKAHASHI, KAZUHIKO, KOHDA, KOHFUKU HUANG, KAWAZOE, YUTAKA

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1983

File:

PDF, 713 KB

1983

30

Potentiation of the Cytotoxicity of Chloroethylnitrosourea by O6-Arylmethylguanines.

KOHDA, Kohfuku, TERASHIMA, Isamu, KOYAMA, Ken-ichi, WATANABE, Katsuo, MINEURA, Katsuyoshi

Journal:

Biological & Pharmaceutical Bulletin

Year:

1995

File:

PDF, 1.13 MB

1995

31

Reactions of 1-methylbenzimidazole derivatives with m-chloroperoxybenzoic acid

Toyo Kaiya, Shinsuke Aoyama, Kohfuku Kohda

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 423 KB

english, 1998

32

Efficient identification and quantification of proteins using isotope-coded 1-(6-methylnicotinoyloxy)succinimides by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

Hiroki Tsumoto, Chie Murata, Naoki Miyata, Kohfuku Kohda, Ryo Taguchi

Journal:

Rapid Communications in Mass Spectrometry

Year:

2007

Language:

english

File:

PDF, 218 KB

english, 2007

33

Antitumor Activity and Neutrophil-selective Hematopoietic Toxicity of Busulfan Analogs in Mice

Taketoshi Kato, Yuko Ohta, Yasuko Suzumura, Kohfuku Kohda, Hiroshi Kimoto, Yutaka Kawazoe

Journal:

Year:

1988

File:

PDF, 273 KB

1988

34

Mechanism of Formation of N2-Benzylguanine in the Reaction of 2-Amino-6-chloropurine with Sodium Benzyl Oxide, and Benzylation of Nucleic Acid Bases.

KOYAMA, Ken-ichi, HITOMI, Kenichi, TERASHIMA, Isamu, KOHDA, Kohfuku

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1996

File:

PDF, 762 KB

1996

35

Syntheses and properties of N-aminopyrimidines

Kohfuku Kohda, Isao Kobayashi, Kenji Itano, Shoji Asano, Yutaka Kawazoe

Journal:

Year:

1993

Language:

english

File:

PDF, 847 KB

english, 1993

36

Inhibitory effect of heavy water on mutability of chemically injured Escherichia coli cells

Atsushi Hakura, Kohfuku Kohda, Yutaka Kawazoe

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1987

Language:

english

File:

PDF, 472 KB

english, 1987

37

Cytotoxicity of 1-Amino-4-phenyl-1,2,3,6-tetrahydropyridine and 1-Amino-4-phenylpyridinium Ion, 1-Amino Analogues of MPTP and MPP + , to Clonal Pheochromocytoma PC12 Cells

Kohda, Kohfuku, Noda, Yasuhiro, Aoyama, Shinsuke, Umeda, Michi, Sumino, Tomoe, Kaiya, Toyo, Maruyama, Wakako, Naoi, Makoto

Journal:

Chemical Research in Toxicology

Year:

1998

Language:

english

File:

PDF, 132 KB

english, 1998

38

Studies on chemical carcinogens and mutagens. XXXVII. A simple method to predict ultimate structures of chemical mutagens, and probably carcinogens.

KAWAZOE, YUTAKA, FUJIURA, TOSHIHARU, KOHDA, KOHFUKU

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1986

File:

PDF, 799 KB

1986

39

Synthesis of 7-aminoguanosine and its conversion to 8-substituted derivatives.

Kohda, Kohfuku, Baba, Kunihisa, Kawazoe, Yutaka

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1986

File:

PDF, 431 KB

1986

40

Design, synthesis, and biological activity of novel PPARγ ligands based on rosiglitazone and 15d-PGJ2

Shinya Usui, Takayoshi Suzuki, Yoshifumi Hattori, Kazuma Etoh, Hiroki Fujieda, Makoto Nishizuka, Masayoshi Imagawa, Hidehiko Nakagawa, Kohfuku Kohda, Naoki Miyata

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 195 KB

english, 2005

41

Dealkylation rates of O6-alkyldeoxyguanosine, O4-alkylthymidine and related compounds in an alkyl-transfer system

Kohfuku Kohda, Moriyoshi Yasuda, Noriaki Sawada, Keiji Itano, Yutaka Kawazoe

Journal:

Chemico-Biological Interactions

Year:

1991

Language:

english

File:

PDF, 565 KB

english, 1991

42

Lignified materials as a potential medicinal resource. IV. Dehydrogenation polymers of some phenylpropenoids and their capacity to stimulate polymorphonuclear cell iodination.

SAKAGAMI, Hiroshi, OH-HARA, Toshinari, KOHDA, Kohfuku, KAWAZOE, Yutaka

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1991

File:

PDF, 814 KB

1991

43

Potentiation of the cytotoxic activity of anti-cancer drugs against cultured L1210 cells by Bacillus thuringiensis subsp. israelensis toxin.

YOKOYAMA, YUMI, OHMORI, IWAO, KOHDA, KOHFUKU, KAWAZOE, YUTAKA

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1988

Language:

english

File:

PDF, 1.81 MB

english, 1988

44

Studies on chemical carcinogens and mutagens. XXVII alkylating property of mutagenic N-trimethylsilylmethyl-N-nitrosourea, a silicon-analogue of N-neopentyl-N-nitrosourea, in aqueous media

Shin-ichi Ninomiya, Masakazu Ebie, Atsushi Hakura, Kohfuku Kohda, Yutaka Kawazoe, Takayuki Shioiri

Journal:

Tetrahedron Letters

Year:

1984

Language:

english

File:

PDF, 243 KB

english, 1984

45

Reactions of a series of 1-Aminobenzimidazoles and 1-Amino-3-methylbenzimidazolium chlorides with 2,4-pentanedione

Toyo Kaiya, Shinsuke Aoyama, Kohfuku Kohda

Journal:

Bioorganic & Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 204 KB

english, 2000

46

Ornithine decarboxylase activity and DNA synthesis in rats after long term treatment with butylated hydroxyanisole, sodium saccharin or phenobarbital

Tatematsu, Masae, Mera, Yukinori, Kohda, Kohfuku, Kawazoe, Yutaka, Ito, Nobuyuki

Journal:

Year:

1986

Language:

english

File:

PDF, 464 KB

english, 1986

47

Synthesis and Miscoding Specificity of Oligodeoxynucleotide Containing 8-Phenyl-2‘-deoxyguanosine

Kohda, Kohfuku, Tsunomoto, Hirotaka, Kasamatsu, Toshio, Sawamura, Fumiko, Terashima, Isamu, Shibutani, Shinya

Journal:

Chemical Research in Toxicology

Year:

1997

Language:

english

File:

PDF, 355 KB

english, 1997

48

Cytotoxicity of Fluoroethylating Agents Is Potentiated by O6-Benzylguanine.

TERASHIMA, Isamu, KOHDA, Kohfuku

Journal:

Biological & Pharmaceutical Bulletin

Year:

1996

File:

PDF, 887 KB

1996

49

Studies on chemical carcinogens and mutagens. XXV. Chemoselectivity of alkyl sulfonates toward 4-(p-nitrobenzyl)pyridine (NBP) in phosphate buffer.

NINOMIYA, SHINICHI, KOHDA, KOHFUKU, KAWAZOE, YUTAKA

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

1984

File:

PDF, 779 KB

1984

50

Enhancing effect of O6-alkylguanine derivatives on chloroethylnitrosourea cytotoxicity toward tumor cells

Katsuyoshi Mineura, Ichiro Izumi, Katsuo Watanabe, Masayoshi Kowada, Kohfuku Kohda, Ken-Ich Koyama, Isamu Terashima, Mituo Ikenaga

Journal:

International Journal of Cancer

Year:

1994

Language:

english

File:

PDF, 820 KB

english, 1994

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